Low cost flights from Santo Domingo to Medellin starting at USD111*

Travel from Santo Domingo to Medellin with a simple low-cost flight experience.

Optional
Jun 2026
FromUSD171*
Seen 13 hours ago
Flight Type One Way/Economy
Jul 2026
FromUSD134*
Seen 8 hours ago
Flight Type One Way/Economy
Aug 2026
FromUSD118*
Seen 13 hours ago
Flight Type One Way/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label USD134
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    • RangeUSD134-USD361

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Get the best deals on cheap flights from Santo Domingo to Medellin

    Get the best deals on cheap flights from Santo Domingo to Medellin
    From
    To
    Fare Type
    Dates
    Price
    Santo Domingo (SDQ)Medellin (MDE)One way
    /
    Economy    		Depart 02/20/2027

    From

    USD111

    Seen 22 hours ago

    Santo Domingo (SDQ)Medellin (MDE)One way
    /
    Economy    		Depart 01/19/2027

    From

    USD111

    Seen 1 hour ago

    Santo Domingo (SDQ)Medellin (MDE)One way
    /
    Economy    		Depart 12/31/2026

    From

    USD111

    Seen 1 day ago

    Santo Domingo (SDQ)Medellin (MDE)One way
    /
    Economy    		Depart 03/23/2027

    From

    USD125

    Seen 13 hours ago

    *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply.

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